The AJCC/UICC staging system is a major tool in oncology, currently used worldwide for clinical, pathological and recurrent disease staging. Squamous cell carcinomas (SCC) of the head and neck are a heterogeneous disease. The TNM classification offers a reliable method for estimating the prognosis of patients with cancer based on certain characteristics of the tumor.
Segmental mandibulectomy impairs health-related quality of life (QoL), by altering speech, mastication, swallowing, and facial aesthetics. Fibula free flap (FFF) used for mandible reconstruction is known to improve outcomes; however, minimal information exists...
Although chemoradiotherapy (CRT) has improved disease outcomes in advanced head and neck cancer (aHNC), toxicity remains a major concern. Treatment interruptions and decreased quality of life (QOL) can occur due to malnutrition, secondary to mucositis, dysphagia and odynophagia. Gastrostomy tubes are used in many patients to improve nutrition during CRT. The optimal timing of PEG placement in patients with aHNC undergoing CRT remains controversial.
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